220509-74-0
Chemical Structure
MMPSI
- CAS No.: 220509-74-0
- Formula:C14H16N2O5S
- Molecular Weight:324.35
IUPAC Name: (S)-5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione
InChIKey: SLQMNVJNDYLJSF-VIFPVBQESA-N
SMILES: O=C1NC2=C(C=C(S(=O)(N3[C@H](COC)CCC3)=O)C=C2)C1=O
Biological Activity: MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MMPSI | 99.09% | MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection. | ||||||||||||||||||||
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MMPSI (Standard) | ≥98% | MMPSI (Standard) is the analytical standard of MMPSI (HY-103346). This product is intended for research and analytical applications. MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection. | ||||||||||||||||||||
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Keywords
