VT101
VT101 is a TEAD inhibitor with an IC50 of 454 nM. VT101 is applicable for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 65194-64-1
- Formula: C14H20N2O4S
- Molecular Weight:312.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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TEAD 454 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H2052 | IC50 |
3 μM
Compound: 39; VT101
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Antiproliferative activity against human NCI-H2052 cells
Antiproliferative activity against human NCI-H2052 cells
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[PMID: 39047607] |
VT101 inhibits YAP-mediated transcriptional activity with an IC50 of 454 nM in a luciferase reporter assay but does not significantly inhibit the growth of NCI-H2052 cells (IC50 > 3 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65194-64-1
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Molecular Weight 312.38
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Formula C14H20N2O4S
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SMILES
O=C(C1=CC(S(=O)(N)=O)=CC=C1NC2CCCCC2)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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