2247544-02-9
Chemical Structure
WS-383
- CAS No.: 2247544-02-9
- Formula:C18H21Cl2N9S2
- Molecular Weight:498.46
IUPAC Name: 2-(5-((2-((4-chlorobenzyl)thio)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)thio)-1H-tetrazol-1-yl)-N,N-dimethylethan-1-amine hydrochloride
InChIKey: LJZUAAKUJAXXHQ-UHFFFAOYSA-N
SMILES: CN(C)CCN1N=NN=C1SC2=CC(C)=NC3=NC(SCC4=CC=C(Cl)C=C4)=NN23.Cl
Biological Activity: WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WS-383 | 99.43% | WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2. | ||||||||||||||||||||
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Similarity Score 0.99
HY-126075WS-383 free base -
Similarity Score 0.91
HY-161470WS-384 -
Similarity Score 0.52
HY-162938Skp2 inhibitor 3 -
Similarity Score 0.51
HY-142694DCN1-UBC12-IN-2 -
Similarity Score 0.49
HY-142692DCN1-UBC12-IN-3 -
Similarity Score 0.48
HY-142691DCN1-UBC12-IN-1 -
Similarity Score 0.46
HY-146323Antitumor agent-58 -
Similarity Score 0.46
HY-182253WS-691 -
Similarity Score 0.45
HY-181476α-Glucosidase-IN-113 -
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