2258671-41-7
2258671-41-7
Chemical Structure
Zharp1-211
- CAS No.: 2258671-41-7
- Formula:C24H25N5O4
- Molecular Weight:447.49
InChIKey: WSAWIHZNHHASBP-UHFFFAOYSA-N
SMILES: O=C(OC1CCOCC1)N2C3=CC(C(C=C4)=CN5C4=NC(NC(C6CC6)=O)=C5)=CN=C3CC2
Biological Activity: Zharp1-211 is a RIPK1 kinase inhibitor with an EC50 of 53 nM and a Kd of 8.7 nM. Zharp1-211 reduces IFN-γ-induced STAT1 activation. Zharp1-211 can be used in the research of graft-versus-host disease and colon cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zharp1-211 | 99.15% | Zharp1-211 is a RIPK1 kinase inhibitor with an EC50 of 53 nM and a Kd of 8.7 nM. Zharp1-211 reduces IFN-γ-induced STAT1 activation. Zharp1-211 can be used in the research of graft-versus-host disease and colon cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-160169Vibilsertib -
Similarity Score 0.58
HY-160170Necrosis inhibitor 3 -
Similarity Score 0.57
HY-144276RIPK1-IN-11 -
Similarity Score 0.52
HY-144277RIPK1-IN-12 -
Similarity Score 0.49
HY-147771ZLWT-37 -
Similarity Score 0.48
HY-139653IDO-IN-14 -
Similarity Score 0.47
HY-151436ZLMT-12 -
Similarity Score 0.47
HY-128348PK68 -
Similarity Score 0.47
HY-156102c-ABL-IN-5 -
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