2376187-16-3

SJF620 Chemical Structure
2376187-16-3

Chemical Structure

SJF620

  • CAS No.: 2376187-16-3
  • Formula:C41H44N8O7
  • Molecular Weight:760.84

IUPAC Name: 3-(5-(2-(2-(2-(4-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethoxy)ethoxy)ethoxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

InChIKey: UJJYPBWMGIPXOE-UHFFFAOYSA-N

SMILES: O=C(C(N(CC1=C2C=CC(OCCOCCOCCN3CCC(N4N=C(C5=CC=C(OC6=CC=CC=C6)C=C5)C7=C(N)N=CN=C74)CC3)=C1)C2=O)CC8)NC8=O

Biological Activity: SJF620 is a PROTAC connected by ligands for Cereblon and Btk with a DC50 of 7.9 nM. SJF620 contains a Lenalidomide analog for recruiting CRBN[1].

Cat. No. Product Name Purity Description Pricing
HY-133137
SJF620 98.01% SJF620 is a PROTAC connected by ligands for Cereblon and Btk with a DC50 of 7.9 nM. SJF620 contains a Lenalidomide analog for recruiting CRBN.
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