2467425-53-0
2467425-53-0
Chemical Structure
Thalidomide-5-O-CH2-COOH
- CAS 番号: 2467425-53-0
- Formula:C15H12N2O7
- Molecular Weight:332.26
IUPAC Name: 4,4'-((2R,3R)-2,3-dimethylbutane-1,4-diyl)bis(2-methoxyphenol)
InChIKey: DTZXDGPVNFRIOU-UHFFFAOYSA-N
SMILES: O=C(O)COC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1
Biological Activity: Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.
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Thalidomide-5-O-CH2-COOH | 95.02% | Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN. | ||||||||||||||||||||
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Keywords
