2467425-53-0
2467425-53-0
Chemical Structure
Thalidomide-5-O-CH2-COOH
- CAS No.: 2467425-53-0
- Formula:C15H12N2O7
- Molecular Weight:332.26
IUPAC Name: 4,4'-((2R,3R)-2,3-dimethylbutane-1,4-diyl)bis(2-methoxyphenol)
InChIKey: DTZXDGPVNFRIOU-UHFFFAOYSA-N
SMILES: O=C(O)COC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1
Biological Activity: Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thalidomide-5-O-CH2-COOH | 95.02% | Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.87
HY-149559Thalidomide-5-O-C2-NH2 hydrochloride -
Similarity Score 0.87
HY-W457950Thalidomide-5-propargyl -
Similarity Score 0.85
HY-W584517Thalidomide-5-O-CH2-COO(t-Bu) -
Similarity Score 0.83
HY-149560Thalidomide-5-O-C3-NH2 hydrochloride -
Similarity Score 0.83
HY-103597Thalidomide-O-COOH -
Similarity Score 0.82
HY-23095RThalidomide-5-OH (Standard) -
Similarity Score 0.82
HY-W457158(S)-Thalidomide-5-OH -
Similarity Score 0.81
HY-149561Thalidomide-5-O-C4-NH2 hydrochloride -
Similarity Score 0.80
HY-46531Thalidomide-5-NH2-CH2-COOH -
Explore the MedChemAI to find more analogs
