26171-23-3
26171-23-3
Chemical Structure
Tolmetin
- CAS No.: 26171-23-3
- Formula:C15H15NO3
- Molecular Weight:257.28
IUPAC Name: 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid
InChIKey: UPSPUYADGBWSHF-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=C(C(C2=CC=C(C)C=C2)=O)N1C
Biological Activity: Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tolmetin | 99.54% | Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Tolmetin (Standard) | ≥98% | Tolmetin (Standard) is the analytical standard of Tolmetin. This product is intended for research and analytical applications. Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Tolmetin-d3 | Tolmetin-d3 is the deuterium labeled Tolmetin. Tolmetin is an orally active and potent COX inhibitor with IC50s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. T D Warner, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7563-8. [Content Brief]
- [2]. DADAŞ, Yakup, et al. Synthesis and anticancer activity of some novel tolmetin thiosemicarbazides. Marmara Pharmaceutical Journal 19(3) • April 2015
