2640677-68-3
Chemical Structure
PARP1-IN-33
- CAS No.: 2640677-68-3
- Formula:C23H24ClFN4O
- Molecular Weight:426.91
InChIKey: VNLWSTOCVHRJSX-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(N2CCN(CCCC3=CC4=C(C(N3)=O)C(F)=CC=C4)CC2)C=C1.Cl
Biological Activity: PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PARP1-IN-33 | 99.02% | PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell). | ||||||||||||||||||||
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Keywords