2640677-68-3

PARP1-IN-33 Chemical Structure
2640677-68-3

Chemical Structure

PARP1-IN-33

  • CAS No.: 2640677-68-3
  • Formula:C23H24ClFN4O
  • Molecular Weight:426.91

InChIKey: VNLWSTOCVHRJSX-UHFFFAOYSA-N

SMILES: N#CC1=CC=C(N2CCN(CCCC3=CC4=C(C(N3)=O)C(F)=CC=C4)CC2)C=C1.Cl

Biological Activity: PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell)[1].

Cat. No. Product Name Purity Description Pricing
HY-164926
PARP1-IN-33 99.02% PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell).
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