2640677-68-3
2640677-68-3
Chemical Structure
PARP1-IN-33
- CAS No.: 2640677-68-3
- Formula:C23H24ClFN4O
- Molecular Weight:426.91
InChIKey: VNLWSTOCVHRJSX-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(N2CCN(CCCC3=CC4=C(C(N3)=O)C(F)=CC=C4)CC2)C=C1.Cl
Biological Activity: PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell)[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PARP1-IN-33 | 99.02% | PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-177100Lotixparib -
Similarity Score 0.56
HY-106781AOPC 4392 hydrochloride -
Similarity Score 0.55
HY-181265PARP1-IN-53 -
Similarity Score 0.55
HY-155616KSK94 -
Similarity Score 0.55
HY-106781OPC-4392 -
Similarity Score 0.55
HY-142657PARP1-IN-7 -
Similarity Score 0.55
HY-100665Dehydroaripiprazole -
Similarity Score 0.54
HY-164031ACloperidone hydrochloride -
Similarity Score 0.54
HY-113575Dehydroaripiprazole hydrochloride -
Explore the MedChemAI to find more analogs
