1. Cell Cycle/DNA Damage Epigenetics
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  3. PARP1-IN-7

PARP1-IN-7 is an inhibitor of poly(ADP-ribose) polymerase-1 (PARP1) as an anticancer agent.

For research use only. We do not sell to patients.

PARP1-IN-7 Chemical Structure

PARP1-IN-7 Chemical Structure

CAS No. : 2084112-75-2

Size Price Stock Quantity
1 mg USD 225 In-stock
5 mg USD 680 In-stock
10 mg USD 1100 In-stock
25 mg USD 2250 In-stock
50 mg USD 3500 In-stock
100 mg USD 5600 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

PARP1-IN-7 is an inhibitor of poly(ADP-ribose) polymerase-1 (PARP1) as an anticancer agent.

Molecular Weight

397.47

Formula

C24H23N5O

CAS No.
Unlabeled CAS

Appearance

Solid

Color

Off-white to light brown

SMILES

N#CC1=CC=C(N2CCN([C@H]3C=C(C4=CC5=C(C(N4)=O)C=CC=N5)CC3)CC2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (251.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5159 mL 12.5796 mL 25.1591 mL
5 mM 0.5032 mL 2.5159 mL 5.0318 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5159 mL 12.5796 mL 25.1591 mL 62.8978 mL
5 mM 0.5032 mL 2.5159 mL 5.0318 mL 12.5796 mL
10 mM 0.2516 mL 1.2580 mL 2.5159 mL 6.2898 mL
15 mM 0.1677 mL 0.8386 mL 1.6773 mL 4.1932 mL
20 mM 0.1258 mL 0.6290 mL 1.2580 mL 3.1449 mL
25 mM 0.1006 mL 0.5032 mL 1.0064 mL 2.5159 mL
30 mM 0.0839 mL 0.4193 mL 0.8386 mL 2.0966 mL
40 mM 0.0629 mL 0.3145 mL 0.6290 mL 1.5724 mL
50 mM 0.0503 mL 0.2516 mL 0.5032 mL 1.2580 mL
60 mM 0.0419 mL 0.2097 mL 0.4193 mL 1.0483 mL
80 mM 0.0314 mL 0.1572 mL 0.3145 mL 0.7862 mL
100 mM 0.0252 mL 0.1258 mL 0.2516 mL 0.6290 mL
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PARP1-IN-7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PARP1-IN-7
Cat. No.:
HY-142657
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