264206-85-1
264206-85-1
Chemical Structure
GSK3987
- CAS No.: 264206-85-1
- Formula:C24H20N2O3
- Molecular Weight:384.43
IUPAC Name: 1-benzyl-3-((4-methoxyphenyl)amino)-4-phenyl-1H-pyrrole-2,5-dione
InChIKey: HLZMYWLMBBLASX-UHFFFAOYSA-N
SMILES: O=C(N(C1=O)CC2=CC=CC=C2)C(NC3=CC=C(C=C3)OC)=C1C4=CC=CC=C4
Biological Activity: GSK3987 is a pan LXRα/β agonist with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK3987 | 99.19% | GSK3987 is a pan LXRα/β agonist with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation. | ||||||||||||||||||||
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References
Keywords
