28166-41-8
Chemical Structure
α-Cyano-4-hydroxycinnamic acid
Synonym(s): α-Cyano-4-hydroxycinnamate
- CAS No.: 28166-41-8
- Formula:C10H7NO3
- Molecular Weight:189.17
IUPAC Name: (E)-2-cyano-3-(4-hydroxyphenyl)acrylic acid
InChIKey: AFVLVVWMAFSXCK-VMPITWQZSA-N
SMILES: O=C(O)/C(C#N)=C/C1=CC=C(O)C=C1
Biological Activity: α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Cyano-4-hydroxycinnamic acid | 99.92% | α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications. | ||||||||||||||||||||
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α-Cyano-4-hydroxycinnamic acid (Standard) | ≥98% | α-Cyano-4-hydroxycinnamic acid (Standard) is the analytical standard of α-Cyano-4-hydroxycinnamic acid (HY-107641). This product is intended for research and analytical applications. α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications. | ||||||||||||||||||||
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α-Cyano-4-hydroxycinnamic acid-d4 | α-Cyano-4-hydroxycinnamic acid-d4 (α-Cyano-4-hydroxycinnamate-d4) is the deuterium labeled α-Cyano-4-hydroxycinnamic acid (HY-107641). α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications. | |||||||||||||||||||||
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References
- [1]. A P Halestrap, et al. The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors. Biochem J. 1975 Apr; 148(1): 85-96. [Content Brief]
- [2]. Sara Granja, et al. The Monocarboxylate Transporter Inhibitor α-cyano-4-hydroxycinnamic Acid Disrupts Rat Lung Branching. Cell Physiol Biochem. 2013;32(6):1845-56. [Content Brief]
