2829263-20-7
Chemical Structure
FPR2 agonist 2
- CAS No.: 2829263-20-7
- Formula:C25H20F2N4O2
- Molecular Weight:446.45
IUPAC Name: isopropyl 3,3-difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylate
InChIKey: KCNMTQVKKFREAN-QFIPXVFZSA-N
SMILES: FC1=CC=C(C=C1)NC(N[C@H](C(N2CCC3=C2C=CC(F)=C3)=O)CC4=CC=C(C=C4)C#N)=O
Biological Activity: FPR2 agonist 2 is a potent and CNS-penetrant FPR2 agonist with an EC50 of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity[1].
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FPR2 agonist 2 | 98.51% | FPR2 agonist 2 is a potent and CNS-penetrant FPR2 agonist with an EC50 of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity. | ||||||||||||||||||||
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Keywords