2842012-69-3
2842012-69-3
Chemical Structure
BAL-0028
- CAS No.: 2842012-69-3
- Formula:C24H22FN3O2
- Molecular Weight:403.45
InChIKey: VTZLXMQBXAOBJF-UHFFFAOYSA-N
SMILES: CN(C(C1=CC(OCC)=C(C2=CC(F)=CC=C2)C=C1)=O)CC3=C4C(C=NN4)=CC=C3
Biological Activity: BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BAL-0028 | 99.86% | BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity. | ||||||||||||||||||||
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