2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. BAL-0028

BAL-0028 (Compound 3) is a NLRP3 activation inhibitor with a IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 has anti-inflammatory activity.

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BAL-0028 Chemical Structure

BAL-0028 Chemical Structure

CAS No. : 2842012-69-3

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BAL-0028 Related Antibodies

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Description

BAL-0028 (Compound 3) is a NLRP3 activation inhibitor with a IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 has anti-inflammatory activity[1].

IC50 & Target

NLRP3

25 nM (IC50)

Molecular Weight

403.45

Formula

C24H22FN3O2
CAS No.
SMILES

CN(C(C1=CC(OCC)=C(C2=CC(F)=CC=C2)C=C1)=O)CC3=C4C(C=NN4)=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BAL-0028 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAL-00282842012-69-3BAL0028BAL 0028NOD-like Receptor (NLR)Anti-inflammationNLRP3Inhibitorinhibitorinhibit

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HY-162333
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