288262-96-4
288262-96-4
Chemical Structure
BX471 hydrochloride
Synonym(s): ZK-811752 hydrochloride
- CAS No.: 288262-96-4
- Formula:C21H25Cl2FN4O3
- Molecular Weight:471.35
IUPAC Name: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride
InChIKey: FRUCNQBAWUHKLS-PFEQFJNWSA-N
SMILES: O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O.Cl
Biological Activity: BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
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BX471 hydrochloride | 99.94% | BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. | ||||||||||||||||||||
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Keywords
