2883495-39-2
Chemical Structure
Enpp/Carbonic anhydrase-IN-2
- CAS No.: 2883495-39-2
- Formula:C23H24FNO4S
- Molecular Weight:429.50
IUPAC Name: 4-cyclopropyl-2-(p-tolyl)pyrimidine-5-carboxylic acid
InChIKey: LLXLLGJJXOHBLG-UHFFFAOYSA-N
SMILES: O=C(C12CC3CC(C2)CC(C1)C3)NC4=CC=C(C=C4)OS(=O)(C5=CC=C(C=C5)F)=O
Biological Activity: Enpp/Carbonic anhydrase-IN-2 (compound 1i) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-2 induces Apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Enpp/Carbonic anhydrase-IN-2 | 98.48% | Enpp/Carbonic anhydrase-IN-2 (compound 1i) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-2 induces Apoptosis. | ||||||||||||||||||||
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-
Similarity Score 0.86
HY-151916Enpp/Carbonic anhydrase-IN-1 -
Similarity Score 0.73
HY-150542Steroid sulfatase-IN-2 -
Similarity Score 0.62
HY-161148FtsZ-IN-9 -
Similarity Score 0.53
HY-169804ENPP3 Inhibitor 1 -
Similarity Score 0.52
HY-158791Enpp-1-IN-21 -
Similarity Score 0.52
HY-121157Chlorfenson -
Similarity Score 0.51
HY-13513U-104 -
Similarity Score 0.50
HY-122765Luxabendazole -
Similarity Score 0.50
HY-121777SFOM-0046 -
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