28882-53-3
28882-53-3
Chemical Structure
(+)-Ochromycinone
Synonym(s): STA-21
- CAS No.: 28882-53-3
- Formula:C19H14O4
- Molecular Weight:306.31
IUPAC Name: (S)-8-hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione
InChIKey: ZAWXOCUFQSQDJS-VIFPVBQESA-N
SMILES: O=C1C[C@@H](C)CC(C1=C2C3=O)=CC=C2C(C4=C3C=CC=C4O)=O
Biological Activity: (+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(+)-Ochromycinone | 98.22% | (+)-Ochromycinone is a natural antibiotic that potently inhibits STAT3. (+)-Ochromycinone is used in the researches of cancers and psoriasis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-18061Ochromycinone -
Similarity Score 0.77
HY-N14432Fujianmycin A -
Similarity Score 0.73
HY-113700PD 116779 -
Similarity Score 0.68
HY-125163MM 47755 -
Similarity Score 0.67
HY-114798Rabelomycin -
Similarity Score 0.66
HY-108993Fujianmycin B -
Similarity Score 0.66
HY-124843LLL3 -
Similarity Score 0.62
HY-W008764Anthrarufin -
Similarity Score 0.60
HY-W6676675-Hydroxyalizarin 1-methyl ether -
Explore the MedChemAI to find more analogs
References
- [1]. Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5. [Content Brief]
- [2]. Miyoshi K, et al. Stat3 as a therapeutic target for the treatment of psoriasis: a clinical feasibility study with STA-21, a Stat3 inhibitor. J Invest Dermatol. 2011 Jan;131(1):108-17. [Content Brief]
