2897696-10-3

PDK-IN-1 Chemical Structure
2897696-10-3

Chemical Structure

PDK-IN-1

  • CAS No.: 2897696-10-3
  • Formula:C20H16BrN7O
  • Molecular Weight:450.29

IUPAC Name: 5-(5-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-6-(5-methoxy-1H-indol-3-yl)-1,2,4-triazin-3-amine

InChIKey: GLYKHSDGYVKDPV-UHFFFAOYSA-N

SMILES: BrC1=CC(C(C2=C(C3=CNC4=C3C=C(OC)C=C4)N=NC(N)=N2)=CN5C)=C5N=C1

Biological Activity: PDK-IN-1 (compound 7o) is a pyruvate dehydrogenase kinase (PDK) inhibitor. PDK-IN-1 shows IC50 values of 0.03 and 0.1 μM for PDK1 and HSP90, respectively. PDK-IN-1 targets PDH/PDK axis thus reducing efficiently the tumor mass[1].

Cat. No. Product Name Purity Description Pricing
HY-149814 		PDK-IN-1 99.74% PDK-IN-1 (compound 7o) is a pyruvate dehydrogenase kinase (PDK) inhibitor. PDK-IN-1 shows IC50 values of 0.03 and 0.1 μM for PDK1 and HSP90, respectively. PDK-IN-1 targets PDH/PDK axis thus reducing efficiently the tumor mass.
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This product is a controlled substance and not for sale in your territory.

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

Keywords