2928093-29-0
2928093-29-0
Chemical Structure
Flonoltinib TFA
Synonym(s): JAK2/FLT3-IN-1 TFA
- CAS No.: 2928093-29-0
- Formula:C27H35F4N7O3
- Molecular Weight:581.61
IUPAC Name: 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl)(methyl)amino)ethan-1-ol 2,2,2-trifluoroacetate
InChIKey: WIIIAEPAIQXSFK-UHFFFAOYSA-N
SMILES: OCCN(C1CCN(C2=CC=C(NC3=NC=C(C)C(C4=CN(C(C)C)N=C4)=N3)C=C2F)CC1)C.O=C(O)C(F)(F)F
Biological Activity: Flonoltinib TFA is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib TFA has anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Flonoltinib TFA | 98.04% | Flonoltinib TFA is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib TFA has anti-cancer activity. | ||||||||||||||||||||
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