2946705-91-3
2946705-91-3
Chemical Structure
PARP7-IN-22
- CAS No.: 2946705-91-3
- Formula:C19H22F6N8O2
- Molecular Weight:508.42
InChIKey: NSSQRFYIKPFOFV-UHFFFAOYSA-N
SMILES: O=C1NN=CC(NCCCCNC(N2CCN(CC2)C3=NC=C(C(F)(F)F)C=N3)=O)=C1C(F)(F)F
Biological Activity: PARP7-IN-22 (XLY-1) is a PARP7 inhibitor with an IC50 of 0.6 nM. PARP7-IN-22 (XLY-1) is orally active, enhances type I interferon signaling in vitro, restores type I interferon signaling, promotes T cell infiltration into tumor tissues, and significantly inhibits tumor growth. PARP7-IN-22 shows promise for research in the field of cancer immunotherapy[1].
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PARP7-IN-22 | 99.59% | PARP7-IN-22 (XLY-1) is a PARP7 inhibitor with an IC50 of 0.6 nM. PARP7-IN-22 (XLY-1) is orally active, enhances type I interferon signaling in vitro, restores type I interferon signaling, promotes T cell infiltration into tumor tissues, and significantly inhibits tumor growth. PARP7-IN-22 shows promise for research in the field of cancer immunotherapy. | ||||||||||||||||||||
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References
Keywords
