3052553-20-2

PROTAC JAK1 degrader 1 Chemical Structure
3052553-20-2

Chemical Structure

PROTAC JAK1 degrader 1

  • CAS No.: 3052553-20-2
  • Formula:C44H41N9O6
  • Molecular Weight:791.85

InChIKey: ZIYSEBHHSBKGIO-UHFFFAOYSA-N

SMILES: O=C(NCC#N)C1=CC=C(C2=NC(NC3=CC=C(N4CCC(C(NCCCCC#CC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)CC4)C=C3)=NC=C2)C=C1

Biological Activity: PROTAC JAK1 degrader 1 is a JAK1 PROTAC degrader with a DC50 of 214 nM and an IC50 of 5.2 nM. PROTAC JAK1 degrader 1 inhibits the downstream JAK-STAT signaling pathway by degrading JAK1. PROTAC JAK1 degrader 1 exhibits antiproliferative activity in cells. PROTAC JAK1 degrader 1 can be used for research on leukemia[1].

Cat. No. Product Name Purity Description Pricing
HY-162608 		PROTAC JAK1 degrader 1 99.97% PROTAC JAK1 degrader 1 is a JAK1 PROTAC degrader with a DC50 of 214 nM and an IC50 of 5.2 nM. PROTAC JAK1 degrader 1 inhibits the downstream JAK-STAT signaling pathway by degrading JAK1. PROTAC JAK1 degrader 1 exhibits antiproliferative activity in cells. PROTAC JAK1 degrader 1 can be used for research on leukemia.
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