PROTAC(H-PGDS)-7
Based on 1 Customer Validation
PROTAC(H-PGDS)-7 is a Hematopoietic prostaglandin D synthase (H-PGDS) molecular glue degrader, with a DC50 of 17.3 pM.
For research use only. We do not sell to patients.
- Purity: 99.42%
- CAS No.: 2761281-50-7
- Formula: C40H38N8O7
- Molecular Weight:742.78
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DP |
Chemical Information
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CAS No. 2761281-50-7
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Appearance Solid
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Molecular Weight 742.78
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Formula C40H38N8O7
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Color Light yellow to yellow
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SMILES
O=C(C1CCN(C2=CC=C(NC(C3=CN=C(OC4=CC=CC=C4)N=C3)=O)C=C2)CC1)N5CCN(C6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (134.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3463 mL | 6.7315 mL | 13.4629 mL | 33.6573 mL |
| 5 mM | 0.2693 mL | 1.3463 mL | 2.6926 mL | 6.7315 mL | |
| 10 mM | 0.1346 mL | 0.6731 mL | 1.3463 mL | 3.3657 mL | |
| 15 mM | 0.0898 mL | 0.4488 mL | 0.8975 mL | 2.2438 mL | |
| 20 mM | 0.0673 mL | 0.3366 mL | 0.6731 mL | 1.6829 mL | |
| 25 mM | 0.0539 mL | 0.2693 mL | 0.5385 mL | 1.3463 mL | |
| 30 mM | 0.0449 mL | 0.2244 mL | 0.4488 mL | 1.1219 mL | |
| 40 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8414 mL | |
| 50 mM | 0.0269 mL | 0.1346 mL | 0.2693 mL | 0.6731 mL | |
| 60 mM | 0.0224 mL | 0.1122 mL | 0.2244 mL | 0.5610 mL | |
| 80 mM | 0.0168 mL | 0.0841 mL | 0.1683 mL | 0.4207 mL | |
| 100 mM | 0.0135 mL | 0.0673 mL | 0.1346 mL | 0.3366 mL |
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