321-55-1
Chemical Structure
Haloxon
- CAS No.: 321-55-1
- Formula:C14H14Cl3O6P
- Molecular Weight:415.59
IUPAC Name: 3-chloro-4-methyl-2-oxo-2H-chromen-7-yl bis(2-chloroethyl) phosphate
InChIKey: KULDXINYXFTXMO-UHFFFAOYSA-N
SMILES: O=P(OCCCl)(OC1=CC=C(C(O2)=C1)C(C)=C(Cl)C2=O)OCCCl
Biological Activity: Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Haloxon | 98.0% | Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium. | ||||||||||||||||||||
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Haloxon (Standard) | ≥98% | Haloxon (Standard) is the analytical standard of Haloxon. This product is intended for research and analytical applications. Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium. | ||||||||||||||||||||
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Esuprone | 99.67% | Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC50 of 7.3 nM. Esuprone can be used for neurological research. | ||||||||||||||||||||
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4-Methylumbelliferyl heptanoate | 98.05% | 4-Methylumbelliferyl heptanoate is a potent fluorometric substrate of lipase. | ||||||||||||||||||||
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Diethylumbelliferyl phosphate | 99.2% | Diethylumbelliferyl phosphate (DEUP) is a broad-spectrum inhibitor of serine esterase and lipases. Diethylumbelliferyl phosphate inhibits cholesteryl ester hydrolase (CEH), adipose triglyceride lipase (ATGL/cytosolic lipase), and retinyl ester hydrolase. Diethylumbelliferyl phosphate blocks the hydrolysis of triglycerides and cholesteryl esters by inhibiting key hydrolases such as CEH and ATGL, thereby inhibiting the mobilization and remodeling of lipid droplet contents, which in turn reduces intracellular reactive oxygen species (ROS) levels and inhibits apoptosis. Diethylumbelliferyl phosphate can be used in research on lipid and cholesterol metabolic diseases and Alzheimer's disease. | ||||||||||||||||||||
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4-Methylumbelliferyl phosphate | 99.84% | 4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant. | ||||||||||||||||||||
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4-Methylumbelliferyl phosphate disodium | 4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant. | |||||||||||||||||||||
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4-Methylumbelliferyl octanoate | 99.82% | 4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase. | ||||||||||||||||||||
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7-(Carboxymethoxy)-4-methylcoumarin | 99.61% | 7-(Carboxymethoxy)-4-methylcoumarin (Compound VIIIa) is the antibacterial and antifungal agent that exhibits inhibitory activity against S. aureus, B. cereus, S. lutea, C. albicans, C. glabrata, and C. parapsilosis. | ||||||||||||||||||||
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4-Methylumbelliferyl phosphate dilithium | 4-Methylumbelliferyl phosphate (dilithium) is a biochemical reagent. | |||||||||||||||||||||
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Coroxon | Coroxon (Coumaphos oxon) is an oxidative metabolite of the organophosphate insecticide Coumaphos (HY-W653717) and an active AChE inhibitor with insecticidal and acaricidal properties. Coroxon can be hydrolyzed by phosphotriesterases of microorganisms such as Nocardia asteroides to produce the fluorescent product Chlorferon. | |||||||||||||||||||||
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References
- [1]. Lyons ET, et, al. Haloxon: critical tests of antiparasitic activity in equids. Am J Vet Res. 1981 Jun;42(6):1043-5. [Content Brief]
- [2]. Hart RJ, et, al. Cholinesterase activities of various nematode parasites and their inhibition by the organophosphate anthelmintic haloxon. Exp Parasitol. 1966 Jun;18(3):332-7. [Content Brief]