329198-87-0
329198-87-0
Chemical Structure
C-178
- CAS No.: 329198-87-0
- Formula:C17H10N2O5
- Molecular Weight:322.27
IUPAC Name: N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide
InChIKey: URUVDCCYSJEGQQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C3C(OC4=CC=CC=C34)=C2
Biological Activity: C-178 is a potent and selective covalent inhibitor of STING. C-178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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C-178 | 99.48% | C-178 is a potent and selective covalent inhibitor of STING. C-178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-112906C-176 -
Similarity Score 0.64
HY-147328LCS3 -
Similarity Score 0.61
HY-168676STING ligand-2 -
Similarity Score 0.60
HY-138682STING-IN-2 -
Similarity Score 0.58
HY-138683STING-IN-3 -
Similarity Score 0.58
HY-148456Anti-inflammatory agent 34 -
Similarity Score 0.57
HY-47709STING ligand-3 -
Similarity Score 0.54
HY-144722Antitubercular agent-12 -
Similarity Score 0.54
HY-163197JSF-2827 -
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