330-55-2
330-55-2
Chemical Structure
Linuron
- CAS No.: 330-55-2
- Formula:C9H10Cl2N2O2
- Molecular Weight:249.09
IUPAC Name: 3-(3,4-dichlorophenyl)-1-methoxy-1-methylurea
InChIKey: XKJMBINCVNINCA-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(Cl)C(Cl)=C1)N(OC)C
Biological Activity:
Linuron is a phenylurea herbicide widely used to control the growth of grasses and weeds in various crops and orchards. Linuron acts as a photosystem II inhibitor. It also functions as a competitive androgen receptor (AR) antagonist, with an EC50 of 200 μM and a Ki of 100 μM against rat AR, and an EC50 of 20 μM against human AR. Linuron exhibits reproductive toxicity in animals and acts as an endocrine disruptor[1][2][3][4].\n
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Linuron | 99.88% | Linuron is a phenylurea herbicide widely used to control the growth of grasses and weeds in various crops and orchards. Linuron acts as a photosystem II inhibitor. It also functions as a competitive androgen receptor (AR) antagonist, with an EC50 of 200 μM and a Ki of 100 μM against rat AR, and an EC50 of 20 μM against human AR. Linuron exhibits reproductive toxicity in animals and acts as an endocrine disruptor.\n |
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Linuron (Standard) | ≥98% | Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor. | ||||||||||||||||||||
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Linuron-d6 | 99.76% | Linuron-d6 is the deuterium labeled Linuron (HY-B1866). Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor. | ||||||||||||||||||||
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Chloranocryl | Chloranocryl (Dicryl) is a herbicide, and is effective when applied at the early growth stage. Chloranocryl has high activity against Brassica rapa and low activity against rice. | |||||||||||||||||||||
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Metallo-β-lactamase-IN-2 | Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7), respectively. | |||||||||||||||||||||
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Metobromuron (Standard) | ≥98% | Metobromuron (Standard) is the analytical standard of Metobromuron. This product is intended for research and analytical applications. Metobromuron is a phenylurea derivative used as a herbicide. | ||||||||||||||||||||
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Diuron (Standard) | 99.44% | Diuron (Standard) is the analytical standard of Diuron (HY-B0860). This product is intended for research and analytical applications. Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research. | ||||||||||||||||||||
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Metoxuron | Metoxuron (Dosanex) is a phenylurea herbicide that effectively targets and controls annual grasses and broadleaf weeds in wheat, barley, and carrot crops. | |||||||||||||||||||||
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Monuron (Standard) | ≥98% | Monuron (Standard) is the analytical standard of Monuron. This product is intended for research and analytical applications. Monuron is a phenylurea herbicide which inhibits photosynthesis. | ||||||||||||||||||||
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Chlorotoluron | 99.91% | Chlorotoluron (Chlortoluron) is a urea herbicide. Chlorotoluron serves as a degradation substrate that undergoes dissipation in soil and produces demethylated chlorotoluron metabolites via N-dealkylation. Chlorotoluron is used for pre-emergence and post-emergence weed control in cereals and various other crops. | ||||||||||||||||||||
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Propanil | 99.91% | Propanil is an orally active immunotoxic Herbicide. Propanil causes delayed and sustained loss of CTL lytic function, as well as irreversible impairment of secondary/tertiary CTL responses. Propanil inhibits PHA-induced increases in IL-10, IFN-gamma, IL-2, and intracellular calcium, as well as anti-CD3-induced IL-10 and IFN-gamma release. Propanil induces splenomegaly, thymic atrophy, bone marrow toxicity, and hemoglobin oxidation. Propanil can be used in research on methemoglobinemia and anemia, as well as liver injury. | ||||||||||||||||||||
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ELP-004 | 99.89% | ELP-004 is a TRPC channel inhibitor and inhibtis TRPC channel-mediated Ca2+ entry. ELP-004 is an osteoclast inhibitor and inhibits osteoclast differentiation. ELP-004 inhibits basal Ca2+ and related NFATc1 translocation in inflammatory osteoclastogenesis. ELP-004 reduces bone erosion in a mouse model of rheumatoid arthritis. | ||||||||||||||||||||
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References
- [1]. Ding H, et al. Reproductive toxicity of linuron following gestational exposure in rats and underlying mechanisms. Toxicol Lett. 2017;266:49-55. [Content Brief]
- [2]. Horemans B, et al. Functional Redundancy of Linuron Degradation in Microbial Communities in Agricultural Soil and Biopurification Systems. Appl Environ Microbiol. 2016;82(9):2843-2853. Published 2016 Apr 18. [Content Brief]
- [3]. Lambright C, et al. Cellular and molecular mechanisms of action of linuron: an antiandrogenic herbicide that produces reproductive malformations in male rats. Toxicol Sci. 2000;56(2):389-399. [Content Brief]
- [4]. Magnucka EG, et al. Various effects of the photosystem II--inhibiting herbicides on 5-n-alkylresorcinol accumulation in rye seedlings. Pestic Biochem Physiol. 2014;116:56-62. [Content Brief]
