ELP-004
Based on 1 Customer Validation
ELP-004 is a TRPC channel inhibitor and inhibtis TRPC channel-mediated Ca2+ entry. ELP-004 is an osteoclast inhibitor and inhibits osteoclast differentiation. ELP-004 inhibits basal Ca2+ and related NFATc1 translocation in inflammatory osteoclastogenesis. ELP-004 reduces bone erosion in a mouse model of rheumatoid arthritis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.89%
- CAS. Nr.: 15533-81-0
- Formel: C10H11Cl2NO
- Molecular Weight:232.11
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 15533-81-0
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Appearance Solid
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Molecular Weight 232.11
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Formel C10H11Cl2NO
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Color Light yellow to yellow
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SMILES
CCC(N(C1=CC(Cl)=C(C=C1)Cl)C)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (215.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3083 mL | 21.5415 mL | 43.0830 mL | 107.7076 mL |
| 5 mM | 0.8617 mL | 4.3083 mL | 8.6166 mL | 21.5415 mL | |
| 10 mM | 0.4308 mL | 2.1542 mL | 4.3083 mL | 10.7708 mL | |
| 15 mM | 0.2872 mL | 1.4361 mL | 2.8722 mL | 7.1805 mL | |
| 20 mM | 0.2154 mL | 1.0771 mL | 2.1542 mL | 5.3854 mL | |
| 25 mM | 0.1723 mL | 0.8617 mL | 1.7233 mL | 4.3083 mL | |
| 30 mM | 0.1436 mL | 0.7181 mL | 1.4361 mL | 3.5903 mL | |
| 40 mM | 0.1077 mL | 0.5385 mL | 1.0771 mL | 2.6927 mL | |
| 50 mM | 0.0862 mL | 0.4308 mL | 0.8617 mL | 2.1542 mL | |
| 60 mM | 0.0718 mL | 0.3590 mL | 0.7181 mL | 1.7951 mL | |
| 80 mM | 0.0539 mL | 0.2693 mL | 0.5385 mL | 1.3463 mL | |
| 100 mM | 0.0431 mL | 0.2154 mL | 0.4308 mL | 1.0771 mL |
ELP-004 Related Classifications
HY-W641445 Related Classifications
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