3542-72-1
3542-72-1
Chemical Structure
Norathyriol
Synonym(s): Mangiferitin
- CAS No.: 3542-72-1
- Formula:C13H8O6
- Molecular Weight:260.20
IUPAC Name: 1,3,6,7-tetrahydroxy-9H-xanthen-9-one
InChIKey: ZHTQCPCDXKMMLU-UHFFFAOYSA-N
SMILES: O=C1C2=C(OC3=C1C=C(O)C(O)=C3)C=C(O)C=C2O
Biological Activity: Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12 μM[1]. Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 µM, 102.4 µM, and 153.5 µM, respectively[2]. Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities.
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Norathyriol | 99.74% | Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12 μM. Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 µM, 102.4 µM, and 153.5 µM, respectively. Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities. | ||||||||||||||||||||
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References
- [1]. Zhi-Long Shi, et al. In Vitro and In Vivo Effects of Norathyriol and Mangiferin on α-Glucosidase. Biochem Res Int. 2017;2017:1206015. [Content Brief]
- [2]. Ashley S Wilkinson,et al. Effects of the mango components mangiferin and quercetin and the putative mangiferin metabolite norathyriol on the transactivation of peroxisome proliferator-activated receptor isoforms. J Agric Food Chem. 2008 May 14;56(9):3037-42. [Content Brief]
