360-68-9
360-68-9
Chemical Structure
Coprostanol
Synonym(s): 5β-Cholestan-3β-ol
- No. CAS: 360-68-9
- Formula:C27H48O
- Molecular Weight:388.67
IUPAC Name: (3S,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: QYIXCDOBOSTCEI-NWKZBHTNSA-N
SMILES: CC(CCC[C@H]([C@H]1CC[C@]2([C@@]3(CC[C@@]4(C[C@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)O)[H])[H])[H])C)C
Biological Activity: Coprostanol (5β-Cholestan-3β-ol) is a fecal sterol formed by microbial reduction of cholesterol in the intestines of man and higher animals. Coprostanol can be used as an indicator sterol of fecal pollution. Coprostanol has been recognized as a good indicator of pollution of water resources by sewage discharges. Coprostanol can serve as a potential biological indicator for cerebral chondrodystrophy (CTX)[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Coprostanol | 99.1% | Coprostanol (5β-Cholestan-3β-ol) is a fecal sterol formed by microbial reduction of cholesterol in the intestines of man and higher animals. Coprostanol can be used as an indicator sterol of fecal pollution. Coprostanol has been recognized as a good indicator of pollution of water resources by sewage discharges. Coprostanol can serve as a potential biological indicator for cerebral chondrodystrophy (CTX). | ||||||||||||||||||||
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Coprostanol (Standard) | ≥98% | Coprostanol (5β-Cholestan-3β-ol) (Standard) is the analytical standard of Coprostanol. This product is used for research and analytical applications. Coprostanol is a fecal sterol formed by the reduction of cholesterol by microorganisms in the human and higher animal intestines. Coprostanol can be used as an indicator sterol for fecal contamination. Coprostanol has been recognized as a good indicator of water resource pollution caused by sewage discharge. Coprostanol can serve as a potential biological indicator for cerebral chondrodystrophy (CTX). | ||||||||||||||||||||
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Coprostanol-d5 | 99.42% | Coprostanol-d5 (5β-Cholestan-3β-ol-d5) is the deuterium labeled Coprostanol. Coprostanol (5β-Cholestan-3β-ol) is a fecal sterol formed by microbial reduction of cholesterol in the intestines of man and higher animals. Coprostanol can be used as an indicator sterol of fecal pollution. Coprostanol has been recognized as a good indicator of pollution of water resources by sewage discharges. Coprostanol can serve as a potential biological indicator for cerebral chondrodystrophy (CTX). | ||||||||||||||||||||
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5α-Cholestan-3β-ol | 99.92% | 5α-Cholestan-3β-ol is a derivitized steroid compound. | ||||||||||||||||||||
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Campestanol | 99.0% | Campestanol is a phytosterol that can be found in plant food. Campestanol lowers serum cholesterol and low-density lipoprotein. Campestanol can be used for the research of metabolic disorders. | ||||||||||||||||||||
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Sitostanol | 99.0% | Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma. | ||||||||||||||||||||
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5α-Cholestane (Standard) | ≥98% | 5α-Cholestane (Standard) is the analytical standard of 5α-Cholestane (HY-133970). This product is intended for research and analytical applications. 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy. | ||||||||||||||||||||
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Allolithocholic acid | 99.69% | Allolithocholic acid is an orally active metabolite of Lithocholic acid (HY-B0172). Allolithocholic acid is a dual GPBAR1 agonist (EC50 = 2.7 μM) and RORγt inverse agonist (IC50 = 3.4 μM). Allolithocholic acid modulates immune and metabolic pathways, regulates immune cell polarization, prevents M1 macrophage and Th17 CD4 cell polarization. Allolithocholic acid improves insulin sensitivity, reduces liver lipid accumulation, reverses liver immunological, inflammatory and metabolic signaling dysregulation, restores bile acid homeostasis, adipose tissue histopathology/function, and intestinal microbiota composition, modulates intestinal immunity. Allolithocholic acid can be used for the researches of cancer, inflammayion, immunology and metabolic disease. | ||||||||||||||||||||
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Stigmastan-3β-ol | 99.70% | Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity. | ||||||||||||||||||||
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Lithocholic acid | 99.96% | Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist. | ||||||||||||||||||||
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Isoallolithocholic acid | 99.84% | Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation. | ||||||||||||||||||||
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5β-Cholestane | 5β-Cholestane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Epicoprostanol | 99.88% | Epicoprostanol is the compound found in adipocere. | ||||||||||||||||||||
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