367273-07-2
367273-07-2
Chemical Structure
AGN-195183
Synonym(s): IRX-5183; VTP-195183; NRX-195183
- CAS No.: 367273-07-2
- Formula:C22H22ClF2NO4
- Molecular Weight:437.86
IUPAC Name: 4-(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carboxamido)-2,6-difluorobenzoic acid
InChIKey: PNAWUIKCVQSLFG-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(F)C=C(NC(C2=C(O)C(Cl)=C3C(C)(C)CCC(C)(C)C3=C2)=O)C=C1F
Biological Activity: AGN-195183 (IRX-5183) is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836. AGN-195183 has no activity on RARβ/γ.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AGN-195183 | 99.75% | AGN-195183 (IRX-5183) is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836. AGN-195183 has no activity on RARβ/γ. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
