36734-19-7
36734-19-7
Chemical Structure
Iprodione
- CAS No.: 36734-19-7
- Formula:C13H13Cl2N3O3
- Molecular Weight:330.17
IUPAC Name: 3-(3,5-dichlorophenyl)-N-isopropyl-2,4-dioxoimidazolidine-1-carboxamide
InChIKey: ONUFESLQCSAYKA-UHFFFAOYSA-N
SMILES: O=C(N(C(N1C2=CC(Cl)=CC(Cl)=C2)=O)CC1=O)NC(C)C
Biological Activity: Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Iprodione | 99.25% | Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Iprodione (Standard) | 98.81% | Iprodione (Standard) is the analytical standard of Iprodione. This product is intended for research and analytical applications. Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Iprodione-d5 | Iprodione-d5 is the deuterium labeled Iprodione. Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Fenobam hydrate | Fenobam hydrate is a selective and orally active mGluR5 antagonist (IC50=84 nM) that can penetrate the blood-brain barrier. Fenobam hydrate shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate has anxiolytic activity, inhibits self-administration behavior in rat, and induces apoptosis in cancer cells. Fenobam hydrate can be used for research on neurological diseases, cancer and drug addiction. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Fenobam (Standard) | ≥98% | Fenobam (Standard) is the analytical standard of Fenobam. This product is intended for research and analytical applications. Fenobam is a selective and orally active mGluR5 antagonist (IC50=84 nM) that can penetrate the blood-brain barrier. Fenobam shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
TT01001 | 99.93% | TT01001 is a selective and orally active mitoNEET agonist and a monoamine oxidase B (MAO-B) inhibitor (IC50 = 8.84 μM). TT01001 does not activate PPARγ but interacts with MitoNEET. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction. TT01001 improves type II diabetes and ameliorates mitochondrial function of mice. TT01001 can used for the studies of type II diabetes and neurological disorders . | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
COH-SR4 | 99.53% | COH-SR4 is an AMPK activator. COH-SR4 shows potent anti-proliferative activities against leukemia, melanoma, breast and lung cancers. COH-SR4 inhibits adipocyte differentiation via AMPK activation. COH-SR4 can be used for the research of obesity and related metabolic disorders. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
VU0155041 | 99.10% | VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(1R,2S)-VU0155041 | 95.09% | (1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyruvate Carboxylase-IN-5 | 98.92% | Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3-(3,5-Dichlorophenyl)-1-methylhydantoin | 95.65% | 3-(3,5-Dichlorophenyl)-1-methylhydantoin is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Procymidone | 99.64% | Procymidone, a pesticide, is an immunogen hapten that can be combined with cOVA (carrier protein) to produce polyclonal antibodies. Procymidone has antifungal activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Reilly C C, et al. The Effects of the Fungicide, Iprodione, on the Mycelium of Sclerotinia sclerotiorum[J]. Phytopathology, 1981, 71(7): 722-727.
- [2]. Griffiths RG, et al. Lipid composition of Botrytis cinerea and inhibition of its radiolabelling by the fungicide iprodione. New Phytol. 2003 Oct;160(1):199-207. [Content Brief]
- [3]. Radice S, et al. Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001 Sep;54(1-2):51-8. [Content Brief]
- [4]. Abd-Elhakim Y M, et al. Iprodione and Chlorpyrifos, Alone and in a Mixture, Impaired Male Fertility and Sexual Behavior in Adult Rats via Suppression of Steroidogenic Genes and SIRT1/TERT/PGC-1α Pathway[J]. 2021.
- [5]. Blystone CR, et al. Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production. Toxicol Lett. 2007 Nov 1;174(1-3):74-81. [Content Brief]
