3947-65-7
3947-65-7
Chemical Structure
Neamine
- CAS No.: 3947-65-7
- Formula:C12H26N4O6
- Molecular Weight:322.36
IUPAC Name: (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol
InChIKey: SYJXFKPQNSDJLI-HKEUSBCWSA-N
SMILES: O[C@H]([C@H]1O)[C@@H]([C@H](C[C@H]1N)N)O[C@H]([C@@H]([C@H]2O)N)O[C@@H]([C@H]2O)CN
Biological Activity: Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Neamine | 99.96% | Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities. | ||||||||||||||||||||
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Neamine (Standard) | ≥98% | Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities. | ||||||||||||||||||||
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Neamine tetrahydrochloride | 99.92% | Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities. | ||||||||||||||||||||
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Ribostamycin | 99.89% | Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI. | ||||||||||||||||||||
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Paromamine | Paromamine is an antibiotic that recognizes ribosomal RNA (rRNA) components. | |||||||||||||||||||||
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3''-Deamino-3''-hydroxykanamycin B | 3''-Deamino-3''-hydroxykanamycin B (NK-1012-1) is a kanamycin antibiotic. 3''-Deamino-3''-hydroxykanamycin B can be produced by S. tenebrarius. 3''-Deamino-3''-hydroxykanamycin B is effective against E. coli ATCC 25922 and E. coli CCARM 1A020, with MIC values of 128 μg/mL. | |||||||||||||||||||||
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Bekanamycin (Standard) | ≥98% | Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain. | ||||||||||||||||||||
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Seldomycin factor 2 | Seldomycin factor 2 (XK 88-2) is an aminoglycoside antibiotic. Seldomycin factor 2 has a broad spectrum of antimicrobial activity. | |||||||||||||||||||||
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Seldomycin factor 3 | Seldomycin factor 3 (XK 88-3) is an aminoglycoside antibiotic. Seldomycin factor 3 has a broad spectrum of antimicrobial activity. | |||||||||||||||||||||
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Sannamycin L | Sannamycin L is an aminoglycoside antibiotic. Sannamycin L has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. | |||||||||||||||||||||
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Mannosyl glucosaminide | Mannosyl glucosaminide is an aminoglycoside antibiotic. Mannosyl glucosaminide has anti-bacterium, mycobacterium and beer yeast effects. | |||||||||||||||||||||
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Deoxystreptamine kanosaminide | Deoxystreptamine kanosaminide is a Tobramycin (HY-B0441) impurity. | |||||||||||||||||||||
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References
- [1]. Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36(1):82-87. [Content Brief]
- [2]. R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85. [Content Brief]
