41983-91-9
Chemical Structure
Glabranine
- CAS No.: 41983-91-9
- Formula:C20H20O4
- Molecular Weight:324.37
IUPAC Name: (S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phenylchroman-4-one
InChIKey: DAWSYIQAGQMLFS-SFHVURJKSA-N
SMILES: O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2O[C@H](C3=CC=CC=C3)C1
Biological Activity: Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus[1]. Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein[2].
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Glabranine | 99.35% | Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus. Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein. | ||||||||||||||||||||
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- [1]. Sánchez I, et al. Antiviral effect of flavonoids on the dengue virus. Phytother Res. 2000 Mar;14(2):89-92. [Content Brief]
- [2]. Ismail NA, et al. Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. Interdiscip Sci. 2017 Dec;9(4):499-511. [Content Brief]
Keywords