434-16-2
434-16-2
Chemical Structure
7-Dehydrocholesterol
- CAS No.: 434-16-2
- Formula:C27H44O
- Molecular Weight:384.64
IUPAC Name: (3S,9S,10R,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: UCTLRSWJYQTBFZ-DDPQNLDTSA-N
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Dehydrocholesterol | 99.97% | 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3. | ||||||||||||||||||||
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7-Dehydrocholesterol (Standard) | ≥98% | 7-Dehydrocholesterol (Standard) is the analytical standard of 7-Dehydrocholesterol. This product is intended for research and analytical applications.7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3. | ||||||||||||||||||||
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7-Dehydrocholesterol-d7 | 98.08% | 7-Dehydrocholesterol-d7 is the deuterium labeled 7-Dehydrocholesterol. 7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3. | ||||||||||||||||||||
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Lumisterol 3 (purity>90%) | 99.24% | Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D. | ||||||||||||||||||||
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Lathosterol | 99.98% | Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury. | ||||||||||||||||||||
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7-Dehydro desmosterol | 7-Dehydro desmosterol is a sterol and an intermediate in cholesterol biosynthesis, which is found in the marine diatom Pseudo-nitzschia multistriata and the nervous system of rodents. | |||||||||||||||||||||
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24(28)-Dehydroergosterol | 94.00% | 24(28)-Dehydroergosterol is a derivative of Episterol. | ||||||||||||||||||||
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5-Dehydroepisterol | 91.96% | 5-Dehydroepisterol is a C28 alkylated sterol based on ergostane, and serves as a major component of the sterol pool in Leishmania parasites. The content of 5-Dehydroepisterol in Leishmania promastigotes can be depleted by 22,26-Azasterol, Amiodarone (HY-14187) and Tomatine (HY-N2166). Among these agents, Amiodarone (HY-14187) inhibits the biosynthetic process of this sterol by disrupting the function of squalene epoxidase. 5-Dehydroepisterol can be used in the research of leishmaniasis and cutaneous leishmaniasis. | ||||||||||||||||||||
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Pyrocholecalciferol | Pyrocholecalciferol, a vitamin D analogue, produced by photochemical transformation of 7-dehydrocholesterol (7-DHC). | |||||||||||||||||||||
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Lumisterol | Lumisterol (9β,10α-Ergosterol) is a photoproduct of 7-dehydrocholesterol, present in the skin, and acts as an orally active VDR non-genomic modulator and ROR inverse agonist. Lumisterol binds to the SARS-CoV-2 Mpro substrate-binding pocket and the RdRP active site, inhibiting enzyme activity. Lumisterol induces NRF2-regulated antioxidant responses, p53 phosphorylation and nuclear translocation, and intracellular free radical scavenging. Lumisterol inhibits the proliferation of epidermal keratinocytes and melanoma cells, modulates cell cycle progression, and suppresses basal and TNFα-induced NFκB transcriptional activity. Lumisterol inhibits RORγ transcriptional activity and IL-17 production. Lumisterol is used in research on UVB-induced skin damage, melanoma, psoriasis, vitamin D deficiency, and COVID-19. | |||||||||||||||||||||
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Ergosterol (Standard) | 99.94% | Ergosterol (Standard) is the analytical standard of Ergosterol. This product is intended for research and analytical applications. Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects. | ||||||||||||||||||||
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22,23-Dihydroergosterol | 70.0% | 22,23-dihydroergosterol is an orally active natural product that can be isolated from Flammulina velutipes. | ||||||||||||||||||||
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Δ7-Stigmasterol | Δ7-Stigmasterol is the major sterols of an amoeba. | |||||||||||||||||||||
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