2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 7-Dehydrocholesterol

7-Dehydrocholesterol 

Cat. No.: HY-113279 Purity: 99.68%
COA Handling Instructions

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

For research use only. We do not sell to patients.

7-Dehydrocholesterol Chemical Structure

7-Dehydrocholesterol Chemical Structure

CAS No. : 434-16-2

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Based on 1 publication(s) in Google Scholar

Other Forms of 7-Dehydrocholesterol:

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Description

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

384.64

Appearance

Solid

Formula

C27H44O
CAS No.
SMILES
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 16.67 mg/mL (43.34 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.83 mg/mL (2.16 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 0.83 mg/mL (2.16 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

7-Dehydrocholesterol434-16-2Endogenous MetaboliteInhibitorinhibitorinhibit

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7-Dehydrocholesterol
Cat. No.:
HY-113279
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