1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 7-Dehydrocholesterol

7-Dehydrocholesterol 

Cat. No.: HY-113279
Handling Instructions

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

For research use only. We do not sell to patients.

7-Dehydrocholesterol Chemical Structure

7-Dehydrocholesterol Chemical Structure

CAS No. : 434-16-2

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100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen[1].

Molecular Weight

384.64

Formula

C₂₇H₄₄O

CAS No.

434-16-2

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 16.67 mg/mL (43.34 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.83 mg/mL (2.16 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 0.83 mg/mL (2.16 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
7-Dehydrocholesterol
Cat. No.:
HY-113279
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