47208-82-2
Chemical Structure
5MPN
- CAS No.: 47208-82-2
- Formula:C15H19N3O4
- Molecular Weight:305.33
IUPAC Name: 5-((8-methoxyquinolin-4-yl)amino)pentyl nitrate
InChIKey: YBOILUNNGBGURC-UHFFFAOYSA-N
SMILES: COC1=C2N=CC=C(NCCCCCO[N+]([O-])=O)C2=CC=C1
Biological Activity: 5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5MPN | 99.89% | 5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines. | ||||||||||||||||||||
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Keywords
