479-18-5
479-18-5
Chemical Structure
Diphylline
Synonym(s): Diprophylline
- CAS No.: 479-18-5
- Formula:C10H14N4O4
- Molecular Weight:254.25
IUPAC Name: 7-(2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: KSCFJBIXMNOVSH-UHFFFAOYSA-N
SMILES: O=C(N1C)N(C)C2=C(N(CC(O)CO)C=N2)C1=O
Biological Activity: Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema[1][2].
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Diphylline | 99.22% | Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema. | ||||||||||||||||||||
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Diphylline (Standard) | 99.22% | Diphylline (Standard) is the analytical standard of Diphylline. This product is intended for research and analytical applications. Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-B1742RProxyphylline (Standard) -
Similarity Score 0.84
HY-B1209REtofylline (Standard) -
Similarity Score 0.83
HY-119440Xanthinol -
Similarity Score 0.82
HY-155944Isbufylline -
Similarity Score 0.80
HY-B1505RAcefylline (Standard) -
Similarity Score 0.75
HY-114531Lomifylline -
Similarity Score 0.74
HY-105762Etamiphyllin -
Similarity Score 0.74
HY-121985Protheobromine -
Similarity Score 0.74
HY-B0004RDoxofylline (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21. [Content Brief]
- [2]. Yosry El-said, et al. In-vitro evaluation of sustained-release dyphylline tablets. Drug Development and Industrial Pharmacy. Volume 17, 1991 - Issue 2
