480-43-3
480-43-3
Chemical Structure
Isosakuranetin
- CAS No.: 480-43-3
- Formula:C16H14O5
- Molecular Weight:286.28
IUPAC Name: (S)-5,7-dihydroxy-2-(4-methoxyphenyl)chroman-4-one
InChIKey: HMUJXQRRKBLVOO-AWEZNQCLSA-N
SMILES: O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(O)=CC(O)=C13
Biological Activity: Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3].
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Isosakuranetin | 99.96% | Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-N2131A(R)-Isosakuranetin -
Similarity Score 0.92
HY-118484(RS)-Sakuranetin -
Similarity Score 0.92
HY-N3006Sakuranetin -
Similarity Score 0.89
HY-N1116Tsugafolin -
Similarity Score 0.89
HY-N18014Naringenin 4',7-dimethyl ether -
Similarity Score 0.89
HY-N0100Naringenin -
Similarity Score 0.89
HY-W011641R(±)-Naringenin (Standard) -
Similarity Score 0.88
HY-N26835-O-Methylnaringenin -
Similarity Score 0.84
HY-N183635,7-Naringenin dimethyl ether -
Explore the MedChemAI to find more analogs
References
- [1]. Drira R, et al. Isosakuranetin, a 4'-O-methylated flavonoid, stimulates melanogenesis in B16BL6 murine melanoma cells. Life Sci. 2015 Dec 15;143:43-9. [Content Brief]
- [2]. Jia S, et al. Antinociceptive Effects of Isosakuranetin in a Rat Model of Peripheral Neuropathy. Pharmacology. 2017;100(3-4):201-207. [Content Brief]
- [3]. Straub I, et al. Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo. Mol Pharmacol. 2013 Nov;84(5):736-50. [Content Brief]
