526-99-8
526-99-8
Chemical Structure
Mucic acid
- CAS No.: 526-99-8
- Formula:C6H10O8
- Molecular Weight:210.14
IUPAC Name: (2R,3S,4R,5S)-2,3,4,5-tetrahydroxyhexanedioic acid
InChIKey: DSLZVSRJTYRBFB-DUHBMQHGSA-N
SMILES: O[C@H]([C@@H](O)C(O)=O)[C@@H](O)[C@H](O)C(O)=O
Biological Activity: Mucic acid is an aldonic acid that can be prepared from pectin. Mucic acid increases the expression level of Runx2, promotes osteoblast differentiation, and upregulates osteogenic differentiation marker genes. Mucic acid can be used to prepare platform compounds, polymers, polymer materials and metal-organic frameworks. Mucic acid is applicable to the research of bone-related defects[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mucic acid | 99.36% | Mucic acid is an aldonic acid that can be prepared from pectin. Mucic acid increases the expression level of Runx2, promotes osteoblast differentiation, and upregulates osteogenic differentiation marker genes. Mucic acid can be used to prepare platform compounds, polymers, polymer materials and metal-organic frameworks. Mucic acid is applicable to the research of bone-related defects. | ||||||||||||||||||||
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Mucic acid (Standard) | ≥98% | Mucic acid (Standard) is the analytical standard of Mucic acid (HY-W014410). This product is intended for research and analytical applications. Mucic acid is an aldonic acid that can be prepared from pectin. Mucic acid increases the expression level of Runx2, promotes osteoblast differentiation, and upregulates osteogenic differentiation marker genes. Mucic acid can be used to prepare platform compounds, polymers, polymer materials and metal-organic frameworks. Mucic acid is applicable to the research of bone-related defects. | ||||||||||||||||||||
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Galactonic acid | Galactonic acid is a metabolite of Galactose. Galactose is converted into Galactonic acid in vivo. Galactonic acid can be used in galactosemia research. | |||||||||||||||||||||
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D-Glucaric acid potassium | 98.0% | D-Glucaric acid potassium (Potassium D-glucarate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid potassium is present in a variety of fruits and vegetables. D-Glucaric acid potassium has cholesterol-lowering and anti-tumor activities. D-Glucaric acid potassium can inhibit tumor cell proliferation and inflammation, and induce apoptosis. | ||||||||||||||||||||
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D-Mannuronic acid | D-Mannuronic acid is an aldonic acid formed by the oxidation of D-mannose, and it is a monosaccharide derivative. D-Mannuronic acid is found in alginates of various seaweeds, including Macrocystis pyrifera and Fucus serratus. | |||||||||||||||||||||
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D-Galacturonic acid | 99.92% | D-Galacturonic acid (D-galUA), as the main component of pectin, is abundantly present in plants. The carboxyl group of D-Galacturonic acid can bind to metal cations. D-Galacturonic acid plays an important role in the food industry, pharmaceutical field, and heavy metal removal, among other aspects. | ||||||||||||||||||||
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D-Glucuronic acid (Standard) | 99.93% | D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity. | ||||||||||||||||||||
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Guluronic acid | Guluronic acid (G2013) is an orally active oxidative stress regulator and anti-inflammatory agent that exerts pharmacological effects by down-regulating various pro-inflammatory and oxidative stress-related genes (such as TLR4, NF-κB, iNOS, etc.) and inhibiting the activities of COX-2, MMPs and VEGF. Low-dose Guluronic acid up-regulates the expression of immunoregulatory genes SHIP1 and SOCS1, thereby effectively inhibiting cancer-related inflammation, tumor angiogenesis, cell adhesion and metastasis, while reducing the accumulation of immunosuppressive cells. Guluronic acid significantly prolongs the survival time of tumor-bearing hosts within a concentration range without direct cytotoxicity, demonstrating favorable safety. Guluronic acid has involved in the research of multiple sclerosis, ankylosing spondylitis, breast cancer and other inflammatory diseases. | |||||||||||||||||||||
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L-Guluronic acid | L-Guluronic acid is a coagulation factor X inhibitor. L-Guluronic acid can replace L-Iduronic acid (HY-135197) in the anticoagulant pentasaccharide of heparin-like substances, while retaining the inhibitory activity against factor Xa. L-Guluronic acid can be used in the research of diseases with coagulation disorders such as deep vein thrombosis and pulmonary embolism. | |||||||||||||||||||||
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Saccharic acid | 98.73% | Saccharic acid is a competitive and potent inhibitor of β-glucuronidase. Saccharic acid inhibits glucuronide synthesis. Saccharic acid as an efficient iron chelate to enhance photo-Fenton degradation of organic contaminants. |
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L-Idaric acid | L-Idaric acid is a biochemical assay reagent. | |||||||||||||||||||||
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D-Gluconic acid (solution) (49-53% w/w in water) | 98.0% | D-Gluconic acid (solution) (49-53% w/w in water) is the carboxylic acid by the oxidation with antiseptic and chelating properties. | ||||||||||||||||||||
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References
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[1]. Ashwin B, et al. 3D-poly (lactic acid) scaffolds coated with gelatin and mucic acid for bone tissue engineering. Int J Biol Macromol. 2020 Nov 1;162:523-532.
[Content Brief] -
[2]. Tan H, et al. [Production of mucic acid from pectin-derived D-galacturonic acid: a review]. Sheng Wu Gong Cheng Xue Bao. 2022 Feb 25;38(2):666-677. Chinese.
[Content Brief]
