543700-68-1
543700-68-1
Chemical Structure
BMS-433771
- CAS No.: 543700-68-1
- Formula:C21H23N5O2
- Molecular Weight:377.44
IUPAC Name: 1-cyclopropyl-3-((1-(4-hydroxybutyl)-1H-benzo[d]imidazol-2-yl)methyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one
InChIKey: KSHJXDWYTZJUEI-UHFFFAOYSA-N
SMILES: O=C(N(C1=C2C=CN=C1)CC3=NC4=CC=CC=C4N3CCCCO)N2C5CC5
Biological Activity: BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease[1][2].
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BMS-433771 | 99.84% | BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease. | ||||||||||||||||||||
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References
- [1]. Christopher Cianci, et al. Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J Antimicrob Chemother [Content Brief]
- [2]. Christopher Cianci, et al. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Antimicrob Agents Chemother. 2004 Jul;48(7):2448-54. [Content Brief]
Keywords
