54375-47-2
54375-47-2
Chemical Structure
Calcein Blue
- CAS. Nr.: 54375-47-2
- Formula:C15H15NO7
- Molecular Weight:321.28
IUPAC Name: 2,2'-(((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)azanediyl)diacetic acid
InChIKey: RJPSHDMGSVVHFA-UHFFFAOYSA-N
SMILES: O=C(O)CN(CC(O)=O)CC1=C(O2)C(C(C)=CC2=O)=CC=C1O
Biological Activity: Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Calcein Blue | 97.04% | Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Calcein Blue (Standard) | ≥98% | Calcein Blue (Standard) is the analytical standard of Calcein Blue (HY-101887). This product is intended for research and analytical applications. Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Calcein Blue AM | 99% | Calcein Blue AM is a cell staining agent. Calcein Blue AM serves as a substrate for intracellular esterases, which hydrolyze its acetoxymethyl (AM) ester group to convert the non-fluorescent reagent into fluorescent Calcein Blue. Calcein Blue AM passively penetrates the plasma membrane of both live and dead cells; it is converted into a polar fluorescent product and retained in the cytoplasm of live cells, whereas dead cells cannot retain the dye. Calcein Blue AM exhibits significant dye leakage, and its fluorescence intensity gradually decreases over time. Calcein Blue AM can be used for endpoint-based cell viability assays and short-term cell tracking experiments with a duration of no more than 4 hours. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
AF40431 | 98.09% | AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
γGlu-AMC | 98.65% | γGlu-AMC is an amino acid derivative. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
AChE-IN-98 | AChE-IN-98 (Compound 26) is an AChE inhitibor, with an IC50 value of 7.3 μM for ee AChE. AChE-IN-98 is also a Coumarin (HY-N0709) derivative. AChE-IN-98 can be used in the research of Alzheimer's disease. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-Hydroxycoumarin-4-acetic acid | 98.71% | 7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-Hydroxy-4-methylcoumarin-3-acetic acid | 98.63% | 7-Hydroxy-4-methylcoumarin-3-acetic acid is a growth inhibitor of root. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-Hydroxy-4-methyl-8-nitrocoumarin | 99.71% | 7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
H-Asp(AMC)-OH | 99.75% | H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-(Carboxymethoxy)-4-methylcoumarin | 99.61% | 7-(Carboxymethoxy)-4-methylcoumarin (Compound VIIIa) is the antibacterial and antifungal agent that exhibits inhibitory activity against S. aureus, B. cereus, S. lutea, C. albicans, C. glabrata, and C. parapsilosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
H-GLU-AMC-OH | 98.47% | H-GLU-AMC-OH is an amino acid derivative that can be used as A fluorescent peptide substrate for the determination of aminopeptidase A enzyme activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Seto D, et al. A simple and selective fluorometric assay for dopamine using a calcein blue-Fe2+ complex fluorophore. Talanta. 2012 May 30;94:36-43. [Content Brief]
- [2]. Sankaranarayanan R, et al. A new fluorimetric method for the detection and quantification of siderophores using Calcein Blue, with potential as a bacterial detection tool. Appl Microbiol Biotechnol. 2015 Mar;99(5):2339-49. [Content Brief]
- [3]. G M Huitink, et al. Methyl calcein blue and other analogues of calcein blue. Talanta. 1974 Nov;21(11):1193-202. [Content Brief]
