58002-62-3
58002-62-3
Chemical Structure
Kainic acid hydrate
- CAS No.: 58002-62-3
- Formula:C10H17NO5
- Molecular Weight:231.25
IUPAC Name: (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid hydrate
InChIKey: FZNZRJRSYLQHLT-SLGZUKMRSA-N
SMILES: O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)=C.O
Biological Activity: Kainic acid hydrate is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid hydrate induces seizures[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kainic acid hydrate | 99.80% | Kainic acid hydrate is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid hydrate induces seizures. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-118758γ-Kainylglutamic acid -
Similarity Score 0.74
HY-178851Isodomoic acid E -
Similarity Score 0.59
HY-118481H-Pro-Glu-OH -
Similarity Score 0.58
HY-W130364H-Pro-Asp-OH -
Similarity Score 0.58
HY-124005Prolylisoleucine -
Similarity Score 0.58
HY-W009686H-Pro-Leu-OH -
Similarity Score 0.58
HY-P11202gamma-Glutamylproline -
Similarity Score 0.57
HY-131286Talaglumetad -
Similarity Score 0.57
HY-122450Pyroglutamylleucine -
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References
- [1]. Cincioğlu-Palabiyik M, et al. Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid-induced experimental model of acute seizures in rats. Neuroreport. 2017 Sep 27;28(14):903-909. [Content Brief]
- [2]. Wang Q, et al. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol Neurobiol. 2005;31(1-3):3-16. [Content Brief]
