583-91-5
Chemical Structure
2-Hydroxy-4-(methylthio)butyric acid
- CAS No.: 583-91-5
- Formula:C5H10O3S
- Molecular Weight:150.20
IUPAC Name: 2-hydroxy-4-(methylthio)butanoic acid
InChIKey: ONFOSYPQQXJWGS-UHFFFAOYSA-N
SMILES: O=C(C(CCSC)O)O
Biological Activity: 2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Hydroxy-4-(methylthio)butyric acid | 88.0% | 2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows. | ||||||||||||||||||||
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2-Hydroxyvaleric acid | 99.17% | 2-Hydroxyvaleric acid is a medium chain α-hydroxy fatty acid. 2-Hydroxyvaleric acid is an activator in fat metabolism of palmitic acid-1-C14. 2-hydroxyvaleric acid is also used as a staining agent for measuring tissue-specific Lactate dehydrogenase activity and elevated levels of 2-hydroxyvaleric acid induces lactic acidosis. | ||||||||||||||||||||
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Methionine | 99.92% | Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation. | ||||||||||||||||||||
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DL-Methionine | 98.0% | DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants. | ||||||||||||||||||||
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DL-Methionine-13C | DL-Methionine-13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants. | |||||||||||||||||||||
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L-Methionine (Standard) | 99.95% | L-Methionine (Standard) is the analytical standard of L-Methionine. This product is intended for research and analytical applications. L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity. | ||||||||||||||||||||
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L-Methionine-15N | 99.50% | L-Methionine-15N is the 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. | ||||||||||||||||||||
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L-Methionine-13C | 99.93% | L-Methionine-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. | ||||||||||||||||||||
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L-Methionine-1-13C | 98.0% | L-Methionine-1-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. | ||||||||||||||||||||
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L-Methionine-13C5 | 99.96% | L-Methionine-13C5 is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. | ||||||||||||||||||||
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L-Methionine-13C5,15N | 99.62% | L-Methionine-13C5,15N is the 13C- and 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. | ||||||||||||||||||||
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References
- [1]. Fang Z, et al. Methionine metabolism in piglets Fed DL-methionine or its hydroxy analogue was affected by distribution of enzymes oxidizing these sources to keto-methionine. J Agric Food Chem. 2010 Feb 10;58(3):2008-14. [Content Brief]
- [2]. St-Pierre NR, et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) and its isopropyl ester on milk production and composition by Holstein cows. J Dairy Sci. 2005 Jul;88(7):2487-97. [Content Brief]
- [3]. Noftsger SM, et al. Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) on microbial growth in continuous culture. J Dairy Sci. 2003 Aug;86(8):2629-36. [Content Brief]
- [4]. Piepenbrink MS, et al. Feeding 2-hydroxy-4-(methylthio)-butanoic acid to periparturient dairy cows improves milk production but not hepatic metabolism. J Dairy Sci. 2004 Apr;87(4):1071-84. [Content Brief]
- [5]. Zhang Q, et al. The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis. J Dairy Sci. 2016 Oct;99(10):8451-8460. [Content Brief]