586379-66-0
586379-66-0
Chemical Structure
PH-797804
- CAS No.: 586379-66-0
- Formula:C22H19BrF2N2O3
- Molecular Weight:477.30
IUPAC Name: 3-(3-bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide
InChIKey: KCAJXIDMCNPGHZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(N2C(C)=CC(OCC3=CC=C(C=C3F)F)=C(C2=O)Br)=C1)C)NC
Biological Activity: PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PH-797804 | 98.94% | PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2. | ||||||||||||||||||||
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PH-797804 (Standard) | ≥98% | PH-797804 (Standard) is the analytical standard of PH-797804 (HY-10403). This product is intended for research and analytical applications. PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2. | ||||||||||||||||||||
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