596-85-0
596-85-0
Chemical Structure
Manool
- CAS No.: 596-85-0
- Formula:C20H34O
- Molecular Weight:290.48
IUPAC Name: (R)-3-methyl-5-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)pent-1-en-3-ol
InChIKey: CECREIRZLPLYDM-QGZVKYPTSA-N
SMILES: CC(CCC1)(C)[C@]([C@@]1(C)[C@H]2CC[C@](O)(C)C=C)([H])CCC2=C
Biological Activity: Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Manool | 99.88% | Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Albicanol | Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress Profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(+)-cis-Abienol | 99.54% | (+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Sclareol | 99.84% | Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
13-Epimanool | 13-Epimanool is the compound isolated from the bark of the Taiwan hemlock. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
13-Hydroxylabda-8(17),14-dien-18-oic acid | 13-Hydroxylabda-8(17),14-dien-18-oic acid is a natural diterpene. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(12Z)-Labda-8(17),12-diene-14,15,16-triol | (12Z)-Labda-8(17),12-diene-14,15,16-triol is a natural diterpene. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Drim-9(11)-en-8α-ol | Drim-9(11)-en-8α-ol is a pimarane-type sesquiterpenol. Drim-9(11)-en-8α-ol can be generated via saponification of drim-9(11)-en-8α-yl acetate. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
trans-Communol | trans-Communol is a labdane diterpenoid, can be isolated from the aerial parts of Salvia cinnabarina. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Drimenol | Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Larixol | 95.52% | Larixol is an fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation. Larixol can interfere with the interaction between the βγ subunit of the fMLP receptor Gi protein and its downstream molecules, thereby inhibiting fMLP-induced respiratory burst. Larixol inhibits fMLP (0.1 μM)-induced superoxide anion production (IC50: 1.98 μM), cathepsin G release (IC50: 2.76 μM), and chemotaxis. Larixol improves neutrophil hyperactivation and reduces inflammation or tissue damage. A series of Larixol derivatives were found to have inhibitory effects on FSGS-related TRPC6 functional mutants. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
