13-Epimanool
13-Epimanool is the compound isolated from the bark of the Taiwan hemlock.
For research use only. We do not sell to patients.
- CAS No.: 1438-62-6
- Formula: C20H34O
- Molecular Weight:290.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>100 μg/mL
Compound: 52
|
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
|
[PMID: 20022253] |
| LoVo | IC50 |
>25 μg/mL
Compound: 52
|
Antiproliferative activity against human LoVo cells
Antiproliferative activity against human LoVo cells
|
[PMID: 20022253] |
| QGY-7703 | IC50 |
>25 μg/mL
Compound: 52
|
Antiproliferative activity against human QGY7703 cells
Antiproliferative activity against human QGY7703 cells
|
[PMID: 20022253] |
| RAW264.7 | IC50 |
11 μg/mL
Compound: 52
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
|
[PMID: 20022253] |
| RAW264.7 | IC50 |
32.3 μg/mL
Compound: 8
|
Cytotoxicity against mouse RAW264.7 cells
Cytotoxicity against mouse RAW264.7 cells
|
[PMID: 19435338] |
| RAW264.7 | IC50 |
9.6 μg/mL
Compound: 8
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production
|
[PMID: 19435338] |
Chemical Information
-
CAS No. 1438-62-6
-
Molecular Weight 290.48
-
Formula C20H34O
-
SMILES
C[C@]([C@H]1CC[C@](C)(O)C=C)(CCC2)[C@](CCC1=C)([H])C2(C)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)