60-89-9
Chemical Structure
Mepazine
Synonym(s): Pecazine
- CAS. Nr.: 60-89-9
- Formula:C19H22N2S
- Molecular Weight:310.46
IUPAC Name: 10-((1-methylpiperidin-3-yl)methyl)-10H-phenothiazine
InChIKey: CBHCDHNUZWWAPP-UHFFFAOYSA-N
SMILES: CN1CC(CCC1)CN2C3=C(SC4=CC=CC=C24)C=CC=C3
Biological Activity: Mepazine (Pecazine) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis[1].
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Mepazine | 99.71% | Mepazine (Pecazine) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis. | ||||||||||||||||||||
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Keywords