6197-39-3
6197-39-3
Chemical Structure
Guvacoline hydrochloride
- CAS No.: 6197-39-3
- Formula:C7H12ClNO2
- Molecular Weight:177.63
IUPAC Name: methyl 1,2,5,6-tetrahydropyridine-3-carboxylate hydrochloride
InChIKey: ZWALOEQHJRUTKM-UHFFFAOYSA-N
SMILES: O=C(C1=CCCNC1)OC.[H]Cl
Biological Activity:
Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal muscarinic receptors[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Guvacoline hydrochloride | 98.0% | Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal muscarinic receptors. |
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Structural Analogs
-
Similarity Score 0.96
HY-116490Guvacoline hydrobromide -
Similarity Score 0.86
HY-N9407Guvacine ethyl ester -
Similarity Score 0.85
HY-100809Guvacine hydrochloride -
Similarity Score 0.83
HY-B0489AArecoline hydrochloride -
Similarity Score 0.82
HY-N2482Guvacine -
Similarity Score 0.82
HY-N2482AGuvacine hydrobromide -
Similarity Score 0.81
HY-N2364Arecoline -
Similarity Score 0.81
HY-B0489RArecoline hydrobromide (Standard) -
Similarity Score 0.78
HY-100810Isoguvacine hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Jiao Wu, et al. Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. J Plant Res. 2019 Jul;132(4):531-540. [Content Brief]
- [2]. M Wolf-Pflugmann, et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittelforschung. 1989 May;39(5):539-44. [Content Brief]
