62014-87-3
62014-87-3
Chemical Structure
Helichrysetin
- CAS No.: 62014-87-3
- Formula:C16H14O5
- Molecular Weight:286.28
IUPAC Name: (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
InChIKey: OWGUBYRKZATRIT-QPJJXVBHSA-N
SMILES: O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=C(O)C=C2
Biological Activity: Helichrysetin is isolated from the flower Helichrysum odoratissimum. Helichrysetin is an ID2 (DNA binding inhibitor 2) inhibitor. Helichrysetin induces apoptosis. Helichrysetin has anti-tumor and antioxidant activity[1][2][3].
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Helichrysetin | 99.86% | Helichrysetin is isolated from the flower Helichrysum odoratissimum. Helichrysetin is an ID2 (DNA binding inhibitor 2) inhibitor. Helichrysetin induces apoptosis. Helichrysetin has anti-tumor and antioxidant activity. | ||||||||||||||||||||
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Helichrysetin (Standard) | ≥98% | Helichrysetin (Standard) is the analytical standard of Helichrysetin. This product is intended for research and analytical applications. Helichrysetin is isolated from the flower Helichrysum odoratissimum. Helichrysetin is an ID2 (DNA binding inhibitor 2) inhibitor. Helichrysetin induces apoptosis. Helichrysetin has anti-tumor and antioxidant activity. | ||||||||||||||||||||
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References
- [1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90. [Content Brief]
- [2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257. [Content Brief]
- [3]. Wang P, et al. Helichrysetin inhibits gastric cancer growth by targeting c-Myc/PDHK1 axis-mediated energy metabolism reprogramming. Acta Pharmacol Sin. 2022 Jun;43(6):1581-1593. [Content Brief]
