630-93-3
630-93-3
Chemical Structure
Phenytoin sodium
Synonym(s): 5,5-Diphenylhydantoin sodium salt
- CAS No.: 630-93-3
- Formula:C15H11N2NaO2
- Molecular Weight:274.25
IUPAC Name: sodium 4-oxo-5,5-diphenyl-4,5-dihydro-1H-imidazol-2-olate
InChIKey: FJPYVLNWWICYDW-UHFFFAOYSA-M
SMILES: O=C1N=C(O[Na])NC1(C2=CC=CC=C2)C3=CC=CC=C3
Biological Activity: Phenytoin sodium (5,5-Diphenylhydantoin sodium salt) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[1][2].
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Phenytoin sodium | 99.78% | Phenytoin sodium (5,5-Diphenylhydantoin sodium salt) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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Phenytoin sodium (Standard) | 99.94% | Phenytoin (sodium) (Standard) is the analytical standard of Phenytoin (sodium). This product is intended for research and analytical applications. Phenytoin sodium (5,5-Diphenylhydantoin sodium salt) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-B0448RPhenytoin (Standard) -
Similarity Score 0.73
HY-B0448S1Phenytoin-15N2,13C -
Similarity Score 0.65
HY-1215955,5-Diphenylbarbituric acid -
Similarity Score 0.65
HY-1456715-(3-hydroxyphenyl)-5-phenylhydantoin -
Similarity Score 0.58
HY-B1657Fosphenytoin -
Similarity Score 0.58
HY-W023985R2-Amino-2,2-diphenylacetic acid (Standard) -
Similarity Score 0.57
HY-101605Prodipine hydrochloride -
Similarity Score 0.57
HY-B1657AFosphenytoin disodium -
Similarity Score 0.57
HY-W001601ABudipine hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Michaela Nelson, et al. The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis. Mol Cancer. 2015 Jan 27;14(1):13. [Content Brief]
- [2]. Rogawski, M.A. and W. Loscher, The neurobiology of antiepileptic drugs. Nat Rev Neurosci, 2004. 5(7): p. 553-64. [Content Brief]
