64208-32-8
Chemical Structure
CGP 12177 hydrochloride
Synonym(s): (±)-CGP 12177 hydrochloride
- CAS No.: 64208-32-8
- Formula:C14H22ClN3O3
- Molecular Weight:315.80
IUPAC Name: 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride
InChIKey: YQVFCYCTITZLSX-UHFFFAOYSA-N
SMILES: O=C1NC2=C(OCC(O)CNC(C)(C)C)C=CC=C2N1.Cl
Biological Activity: CGP 12177 ((±)-CGP 12177) hydrochloride is a β-Adrenergic receptor (β-AR) ligand. CGP 12177 hydrochloride is a β3-AR (Ki = 88 nM) agonist with β1/β2-AR (Ki = 0.9 nM for β1; Ki = 4 nM for β2) antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CGP 12177 hydrochloride | 99.57% | CGP 12177 ((±)-CGP 12177) hydrochloride is a β-Adrenergic receptor (β-AR) ligand. CGP 12177 hydrochloride is a β3-AR (Ki = 88 nM) agonist with β1/β2-AR (Ki = 0.9 nM for β1; Ki = 4 nM for β2) antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research. | ||||||||||||||||||||
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Keywords
